ABSTRACT
Adequate nutrition in early life is proposed to shape a child’s future health by launching the growth trajectory in the proper direction, which helps to avoid negative metabolic programming effects. Protein intake during infancy and early childhood is of great importance, as it plays a key role in infant metabolic programming and the future risk of obesity. Breastfeeding provides the best nutrition in early life, with many benefits tailored for the baby, including the appropriate quantity and quality of proteins. Considering the high prevalence of childhood, and subsequent adult, obesity in the region, a virtual Middle East expert consensus meeting was held to discuss an effective approach for managing childhood obesity. Leading pediatric experts from Bahrain, Egypt, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates participated in the meeting. The experts discussed, debated, and agreed on certain directions, including the importance of educating parents, endorsing breastfeeding, and ensuring optimum quantity and quality intake of proteins in early life.This expert consensus may serve as the starting point for healthcare professionals in the region who are interested in shaping a healthy future for the generations to come.
ABSTRACT
To investigate the effects of ribavirin on hepatitis C virus [HCV] specific T-helper cell responses and the expression of interleukin-12 receptor-beta-1 and beta-2 chains on CD4+ T cells, peripheral blood mononuclear cells from 56 patients with proven chronic hepatitis C were incubated with or without ribavirin [0.1 mug/ml]. The results suggested that ribavirin induces up-regulation and differentiation of CD4+ T cells through the up-regulation of interleukin-12 receptor beta-2 chain